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As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours.

Most common Tadalafil side effects

  • Headache
  • Indigestion
  • Back pain
  • Muscle pain
  • Flushing
  • Stuffy nose

Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:

  • An erection will not go away (priapism). If you have an erection that lasts longer than 4 hours, get medical help right away. If not treated right away, priapism can permanently damage the penis.
  • Sudden vision loss in one or both eyes. Sudden vision loss can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropath (NAION).
  • Sudden hearing decrease or hearing loss. Some may also have ringing in the eyes (tinnitus) or dizziness.

For a complete list of possible side effects,.

Possible drug interactions

Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat.

On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.

For a complete list of possible drug interactions,.

Other important safety information

Patients who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.

After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.

Note:All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or health care provider.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Other benefits of Tadalafil

  • Patients who have a medical condition called “left ventricular outlet obstruction may have irregular heartbeats” or sudden vision loss.
  • Left ventricular outlet obstruction (ventricular septal defect) is a serious condition that can cause severe pain, possibly on the penis, in a day or two.
  • NAION is a condition that is often mistaken for a heart attack or a heart attack leading to a stroke.

Dosage and direction

How Tadalafil can affect you

Patients should be advised to avoid exercise until the erection has completely gone, with the first four hours before sexual activity informing them if Erectile dysfunction (ED) first occurs. If after four hours, Erectile dysfunction does not occur, patients should be advised to engage in foreplay or foreplaywhich may cause painful erections, lightheadedness, or flushing.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Describing the response to Cialis's effectiveness, its onset of action, and its potential to interact with certain foods and beverages commonly seen with erectile dysfunction. Many people used Cialis at a specific time and time condition, usually around 10 days, even if they had never used it before. However, there are cases where Cialis can be taken more than once daily, and some individuals have reported side effects such as dizziness or heart failure.
  • Cimetidine: The combination of Cialis and its antibiotic methotrexate can cause rapid drops in blood pressure that can be dangerous. It can also increase the risk of heart attack or stroke while using Cialis.
  • Antifungal products (e.g., itraconazole, ketoconazole): It is generally not recommended to take Cialis with this medication because it can cause side effects such as diarrhea or an upset stomach. Always follow your doctor's advice.
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    Tadalafil is a brand name of Cialis and it works by inhibiting the enzyme that increases blood flow to the penis, thus increasing blood flow into the penis. It is available in tablets of 2, 5, and 10 mg. Generic Cialis is the same as the brand name. Tadalafil 5 mg is the same as the brand name. This medication comes in 2.5 mg, 5 mg, 10 mg, and 20 mg tablets. The dose strength of tadalafil is 5 mg. The tablet will be taken once per day and the effects of the medication will persist for 5 consecutive days. The effect of tadalafil will last up to 36 hours. Tadalafil will increase the blood flow into the penis when the blood vessels in the penis become dilated. It will also increase the amount of blood that travels through the penis to the urethra.

    Tadalafil 5mg should not be taken if the patient is taking nitrates. The patient should not take tadalafil or any other nitrates, as the combination of the two is not recommended. The combination of these two can cause a serious condition called angina.

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